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Immunization results in a decrease in BDV nucleic acids. Brain sections from NI and Imm animals at 14, 21, 31, and 36 days after BDV infection were analyzed by ISH with single-stranded RNA probes for detection of BDV N protein mRNA and genomic RNA. The distribution of signal obtained with each probe was indistinguishable. Results from representative sections probed for genomic RNA are shown.
