Table 1.
Baseline characteristics of participants (N = 250) by breast cancer status.
| Categorical Characteristic | Patients, n = 173 N (%) | Controls, n = 77 N (%) | p* |
|---|---|---|---|
| Body Mass Index, kg/m2 | |||
| 20 to <25 (Normal) | 50 (28.9) | 29 (37.7) | 0.41 |
| 25 to <30 (Overweight) | 58 (33.5) | 30 (39.0) | Referent |
| 30+ (Obese) | 63 (36.4) | 18 (23.4) | 0.21 |
| Missing Data | 2 (1.2) | 0 | |
| Comorbidities | |||
| 0 | 92 (53.2) | 39 (50.7) | Referent |
| 1 | 55 (31.8) | 32 (41.6) | 0.30 |
| 2 | 17 (9.8) | 4 (4.2) | 0.32 |
| 3+ | 9 (5.2) | 2 (2.6) | 0.30 |
| Self-Identified Race, Ethnicity | |||
| White, Non-Hispanic | 97 (56.1) | 63 (81.8) | Referent |
| White, Hispanic | 38 (22.0) | 4 (5.2) | 0.0013 |
| Asian | 14 (8.1) | 2 (2.6) | 0.04 |
| Black | 12 (6.9) | 2 (2.6) | 0.05 |
| Other (None of the Above) | 12 (6.9) | 6 (7.8) | 0.57 |
| Education | |||
| Less than High School | 11 (6.4) | 1 (1.3) | 0.21 |
| High School Diploma | 38 (22.0) | 7 (9.1) | 0.33 |
| Some College | 66 (38.2) | 26 (33.8) | Referent |
| Bachelor's Degree | 35 (20.2) | 16 (20.8) | 0.45 |
| Graduate Degree | 23 (13.3) | 27 (35.1) | 0.002 |
| Marital Status | |||
| Never Married | 16 (9.3) | 1 (1.3) | 0.07 |
| Married/Partnered | 108 (62.4) | 59 (76.6) | Referent |
| Divorced | 11 (6.4) | 2 (2.6) | 0.19 |
| Widowed | 32 (18.5) | 14 (18.2) | 0.55 |
| Missing Data | 6 (3.5) | 1 (1.3) | 0.29 |
| Annual Household Income | |||
| Up to $45,000 | 56 (32.4) | 10 (13.0) | 0.001 |
| >$45,000 to >$200,000 | 91 (52.6) | 61 (79.2) | Referent |
| Declined to State | 26 (15.0) | 6 (7.8) | 0.07 |
| Using Anti-inflammatory Medication | 86 (49.7) | 52 (67.5) | 0.02 |
| Continuous |
Patients, n = 173 |
Controls, n = 77 |
p* |
|---|---|---|---|
| Characteristica | Median (Min-Max) | Median (Min-Max) | |
| Age, Years | 60 (45–84) | 61 (45–86) | 0.24 |
| Social Support |
4.50 (1.08–5.00) |
4.42 (1.75–5.00) |
0.52 |
| Inflammatory Markers: | |||
| sTNF-RII, pg/mL | 2171 (1195–9784) | 2215 (1126–4504) | 0.44 |
| IL-6, pg/mL | 1.7 (0.4–33.7) | 1.3 (0.4–6.1) | 0.15 |
| IL-1RA, pg/mL | 310 (98–1606) | 254 (107–1852) | 0.009 |
| C-Reactive Protein§, mg/L | 2.6 (0.2–50.6) | 2.2 (0.2–59.5) | 0.16 |
| Behavioral Symptoms: | |||
| Physical Functioning | 28 (11–30) | 28 (14–30) | 0.06 |
| Pain | 0.10 (0.10–7.25) | 0.10 (0.10–7.00) | 0.63 |
| Attention/concentration | 9.5 (3.5–16.0) | 10.0 (4.0–17.5) | 0.03 |
| Perceived Cognitive Problems | 51 (36–93) | 49 (37–80) | 0.09 |
| Fatigue | 3.67 (0.10–9.00) | 3.33 (0.10–7.00) | 0.92 |
| Sleep Insufficiency | 3.5 (1.6–6.0) | 3.0 (1.0–6.0) | 0.14 |
| Depression | 48 (40–79) | 40 (40–66) | <0.001 |
*p values are from chi-square tests applied to the results of conditional logistic regression. For categorical variables, the most populous category per variable served as the Referent category.
a
For continuous characteristics, raw values are presented, but where their distributions were skewed, p values were obtained using natural log-transformed values.