Table 1.
TMJ layers/areas |
Transcriptional Factors/Intracellular |
||
---|---|---|---|
Localization | |||
NANOG | STAT-3 | SOX-5 | |
Mandibular Condyle | |||
Fibrous Layer | N+C (Strong) | C (Weak) | – |
Proliferative Layer | N+C (Strong) | C (Weak) | C (Weak) |
Chondrocyte Layer | N | N | N |
Hypertrophic Chondrocyte Layer | N | N | N |
Ossification Area (Osteoblast) | C | C | C |
Articular Disc | |||
Fibroblast/fibrocondrocytes | C | N | C (Weak) |
Perivascular | C | N | C (Strong) |
Mandibular Fossa | |||
Dense Conective Layer | C | – | – |
Proliferative Layer | C | C | – |
Ossification Area (Osteoblast) | C | C | C |
(N-nuclear, C-cytoplasmic, N+C similar expression in nucleus and cytoplasm, - no immunostainning).