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. 2023 Aug 14;13(5):636–641. doi: 10.1016/j.jobcr.2023.08.002

Table 1.

Expression of Nanog, Stat 3 and Sox-5 in TMJ analyzed layers/areas.

TMJ layers/areas
Transcriptional Factors/Intracellular
Localization
NANOG STAT-3 SOX-5
Mandibular Condyle
Fibrous Layer N+C (Strong) C (Weak)
Proliferative Layer N+C (Strong) C (Weak) C (Weak)
Chondrocyte Layer N N N
Hypertrophic Chondrocyte Layer N N N
Ossification Area (Osteoblast) C C C
Articular Disc
Fibroblast/fibrocondrocytes C N C (Weak)
Perivascular C N C (Strong)
Mandibular Fossa
Dense Conective Layer C
Proliferative Layer C C
Ossification Area (Osteoblast) C C C

(N-nuclear, C-cytoplasmic, N+C similar expression in nucleus and cytoplasm, - no immunostainning).