Fig. 1.

Characterization of CNS infiltrating and resident myeloid cells upon SCI. A, Myeloid lineage-specific cell isolation protocol used in the study. The illustration depicts the Cremato mouse line FACS only. B–C, UMAPs of the batch corrected dataset separated by strain and fate mapping in the Cx3cr1^CreERT2 and Cremato mouse lines. Each dot represents a cell and is coloured by the time of collection. D, UMAPs with cells (dots) coloured by the gene expression of the listed cell-type markers in the Cremato mouse line. Scale bars are the averaged log₂-transformed counts from the listed marker genes. E, Area plot of the myeloid cell types comprising the Cx3cr1 dataset (left) and UMAP of the entire dataset (right) separated by time point and coloured by cell type.