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. 2023 Aug 11;13:1209799. doi: 10.3389/fonc.2023.1209799

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Copyright © 2023 Yang, Liu, Liu, Zheng, Wu, Zhou, Zheng and Chai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A comparison of the Hematoxylin and eosin staining results from the metastatic subcutaneous nodules and primary lung tumor. Immunohistochemical show that the lung tumor biopsy is (A) squamous cell cancer (B) positive for p40 (C)negative for TTF1 (D) positive for CK7, and metastatic subcutaneous nodules are (E) adenocarcinoma (F) negative for TTF1 (G) negative for Napsin A (H) positive for CK7. (I) Variant allele frequencies (VAF) of gene mutations in different morphological sites. (J) Flow chart of patient treatment.