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. 2023 Aug 11;10:1203009. doi: 10.3389/fcvm.2023.1203009

Table 1.

Comparisons of the baseline clinical and echocardiographic data between the training and the validation cohorts.

Variable Training cohort (n = 232) Validation cohort (n = 100) P-value FDR-adjusted P-value
Age, year 61.56 ± 6.33 61.01 ± 6.49 0.475 0.687a
Gender, n (%) Male 147 (63.4%) 67 (67.0%) 0.525 0.687b
Female 85 (36.6%) 33 (33.0%)
BMI, kg/m2 23.55 ± 3.13 23.11 ± 3.36 0.250 0.605a
Hypertension, n (%) 107 (46.1%) 53 (53.0%) 0.250 0.605b
T2DM, n (%) 35 (15.1%) 18 (18.0%) 0.506 0.687b
Dyslipidemia, n (%) 66 (28.4%) 26 (26.0%) 0.647 0.786b
Smoking, n (%) 60 (25.9%) 32 (32.0%) 0.252 0.605b
AF type PAF 154 (66.4%) 72 (72.0%) 0.314 0.605b
PeAF 78 (33.6%) 28 (28.0%)
AF duration, year 3 (2–4) 3 (2–4) 0.943 0.943c
Antiarrhythmic drugs failure, n (%) 156 (67.2%) 62 (62.0%) 0.356 0.605b
AF recurrence, n (%) 75 (32.3%) 25 (25.0%) 0.182 0.605b
Time to recurrence <6 months 19 (25.3%) 9 (36.0%) 0.304 0.605b
≥6 months 56 (74.7%) 16 (64.0%)
LVEF, % 57.4 (54.2–60.6) 57.3 (54.1–60.7) 0.916 0.943c
LAD, mm 42.0 (38.4–45.9) 43.6 (39.0–46.2) 0.323 0.605c
LAVImax, ml/m2 38.2 (32.8–43.4) 36.7 (32.7–42.4) 0.288 0.605c
LAAFV, cm/s 46.8 (37.2–57.4) 47.5 (39.9–52.8) 0.886 0.943c
PALS, % 24.6 (21.5–28.3) 26.3 (22.3–31.1) 0.142 0.605c

Variables are expressed as median (interquartile range) if they are not normally distributed.

FDR, false discovery rate; BMI, body mass index; T2DM, type 2 diabetes; AF, atrial fibrillation; PAF, paroxysmal atrial fibrillation; PeAF, persistent atrial fibrillation; LVEF, left ventricular ejection fraction; LAD, left atrial diameter; LAVImax, left atrium maximal volume index; LAAFV, left atrial appendage emptying flow velocity; PALS, peak atrial longitudinal strain.

a

For an independent-sample t-test.

b

For a chi-square test.

c

For a Mann–Whitney U test.