Table 1.
Variable | Training cohort (n = 232) | Validation cohort (n = 100) | P-value | FDR-adjusted P-value | |
---|---|---|---|---|---|
Age, year | 61.56 ± 6.33 | 61.01 ± 6.49 | 0.475 | 0.687a | |
Gender, n (%) | Male | 147 (63.4%) | 67 (67.0%) | 0.525 | 0.687b |
Female | 85 (36.6%) | 33 (33.0%) | |||
BMI, kg/m2 | 23.55 ± 3.13 | 23.11 ± 3.36 | 0.250 | 0.605a | |
Hypertension, n (%) | 107 (46.1%) | 53 (53.0%) | 0.250 | 0.605b | |
T2DM, n (%) | 35 (15.1%) | 18 (18.0%) | 0.506 | 0.687b | |
Dyslipidemia, n (%) | 66 (28.4%) | 26 (26.0%) | 0.647 | 0.786b | |
Smoking, n (%) | 60 (25.9%) | 32 (32.0%) | 0.252 | 0.605b | |
AF type | PAF | 154 (66.4%) | 72 (72.0%) | 0.314 | 0.605b |
PeAF | 78 (33.6%) | 28 (28.0%) | |||
AF duration, year | 3 (2–4) | 3 (2–4) | 0.943 | 0.943c | |
Antiarrhythmic drugs failure, n (%) | 156 (67.2%) | 62 (62.0%) | 0.356 | 0.605b | |
AF recurrence, n (%) | 75 (32.3%) | 25 (25.0%) | 0.182 | 0.605b | |
Time to recurrence | <6 months | 19 (25.3%) | 9 (36.0%) | 0.304 | 0.605b |
≥6 months | 56 (74.7%) | 16 (64.0%) | |||
LVEF, % | 57.4 (54.2–60.6) | 57.3 (54.1–60.7) | 0.916 | 0.943c | |
LAD, mm | 42.0 (38.4–45.9) | 43.6 (39.0–46.2) | 0.323 | 0.605c | |
LAVImax, ml/m2 | 38.2 (32.8–43.4) | 36.7 (32.7–42.4) | 0.288 | 0.605c | |
LAAFV, cm/s | 46.8 (37.2–57.4) | 47.5 (39.9–52.8) | 0.886 | 0.943c | |
PALS, % | 24.6 (21.5–28.3) | 26.3 (22.3–31.1) | 0.142 | 0.605c |
Variables are expressed as median (interquartile range) if they are not normally distributed.
FDR, false discovery rate; BMI, body mass index; T2DM, type 2 diabetes; AF, atrial fibrillation; PAF, paroxysmal atrial fibrillation; PeAF, persistent atrial fibrillation; LVEF, left ventricular ejection fraction; LAD, left atrial diameter; LAVImax, left atrium maximal volume index; LAAFV, left atrial appendage emptying flow velocity; PALS, peak atrial longitudinal strain.
For an independent-sample t-test.
For a chi-square test.
For a Mann–Whitney U test.