Mean cloxacillin benzathine (1:1) residue concentrations in foremilk over the first 9 milkings after calving. Milk of udder quarters was grouped based on the interval between treatment and calving into 6 to 17 d (G14d; n = 17; blue), 18 to 24 d (G21d; n = 15; orange), and 25 to 32 d (G28d; n = 13; yellow). Least square estimates (mean ± 95% CI) were used from the repeated measures ANOVA. Cloxacillin benzathine (1:1) residue concentration was affected by the number of milking relative to calving (p < 0.001), interval between treatment and calving (p < 0.001), protein content of the milk (p = 0.015), lactose content of the milk (p < 0.001), and the number of milking relative to calving by interval from treatment to calving (p < 0.066). The dashed line indicates the maximum residue limit. Pairwise comparisons among groups with Bonferroni’s corrected p < 0.05 are marked with the following letters: a = G14d vs. G21d, b = G14d vs. G28d; c = G21d vs. G28d.