Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 12;13(16):2608. doi: 10.3390/ani13162608

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

SLC45A2 and GPNMB promote the deposition of melanin in chicken melanocytes. (A) Marker gene identification in chicken primary melanocytes (scale 50 μm). (B,C) The mRNA expression of SLC45A2 and GPNMB after 48 h of transfection of the SLC45A2 overexpression vector pcDNA3.1-SLC45A2-EGFP and the GPNMB overexpression vector pcDNA3.1-GPNMB-EGFP in melanocytes. (D,E) Effects of SLC45A2 and GPNMB overexpression on the expression of genes related to pigmentation melanocytes. (F,G) Effects of SLC45A2 and GPNMB overexpression on MITF protein levels. (H,I) Effect of SLC45A2 and GPNMB overexpression on the tyrosinase content of melanocytes. (J,K) Effect of SLC45A2 and GPNMB overexpression on the melanin content of melanocytes. * p < 0.05; ** p < 0.01.