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. 2023 Jul 29;12(8):1520. doi: 10.3390/antiox12081520

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© 2023 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Signaling pathways of H₂S production via Hcy metabolism. In the cytoplasm, H₂S is produced from Hcy with the help of the CBS and CSE enzymes, whereas in mitochondria, H₂S is produced with the help of the 3-MST enzyme.