Table 1.
Association of Hyperhomocysteinemia with different disorders.
| Genes | Polymorphisms | Condition | Associated Complications | References |
|---|---|---|---|---|
| CBS | 844INS68 | HHcy | Peripheral artery occlusive disease | [50] |
| T833C | HHcy | Stroke | [51] | |
| 844INS68 | HHcy | Thrombosis | [52] | |
| MTHFR | C677T | HHcy | Retinal vein occlusion | [53] |
| C677T | HHcy | Stroke | [42,43,44,45] | |
| C677T | HHcy | Venous thromboembolism | [54] | |
| C677T | HHcy | Hypertension | [55,56,57] | |
| C677T | HHcy | Alzheimer’s Disease | [58] | |
| A1298C | HHcy | Cerebral venous sinus thrombosis | [59,60,61] | |
| C677T | HHcy | Hyperlipidemia | [62] | |
| C677T | HHcy | Diabetic nephropathy | [63,64,65,66] | |
| C677T | HHcy | Cerebral venous thrombosis | [67] | |
| C677T | HHcy | Parkinson’s Disease | [68,69] |