TABLE 1.

Effects of ampicillin and/or fucoidin treatment on CSF inflammatory indices in pneumococcal meningitis in rabbits^a

Treatment	Concn of:
	Leukocytes (106/liter)		Protein (g/liter)		Lactate (mmol/liter)		Glucose (mmol/liter)
	16 h	20 h	16 h	20 h	16 h	20 h	16 h	20 h
None (control group)	960 ± 326	662 ± 160	1.7 ± 0.7	1.8 ± 0.6	13.1 ± 2.9	11.4 ± 3.5	3.4 ± 0.4	3.1 ± 0.5
Ampicillin	1,456 ± 520	7,687 ± 2,022	2.1 ± 0.9	2.3 ± 0.6	10.5 ± 1.7	11.0 ± 1.7	3.6 ± 0.3	3.5 ± 0.32
Ampicillin and fucoidin	1,994 ± 858	1,505 ± 444b	3.1 ± 1.2	1.6 ± 0.3	10.2 ± 1.9	13.6 ± 2.2	3.7 ± 0.4	3.8 ± 0.5

^aFucoidin (10 mg/kg) and/or ampicillin (40 mg/kg) given i.v. at 16 h. Values are means ± SE. 

^bP < 0.001 versus ampicillin alone at 20 h.