TABLE 3.
Neutralizing antibody seroconversion patterns in children with serologically defined primary rotavirus infections
| Serotypes of infecting virus (no. of samples) | No. of children showing the indicated NtAb seroconversion patterns (GMT)a
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Wa | P | ST3 | Wa, P | P, ST3 | Wa, S2, P | Wa, P, ST3 | Wa, S2, P, ST3 | Total (%) | |
| G3, P1A (47) | 3 (800) | 12 (356) | 0 | 16 (418, 497) | 1 (400, 200) | 2 (1,131, 283, 566) | 3 (317, 1,008, 200) | 1 (1,600, 800, 1,600, 400) | 38 (81) |
| G1, P1A (23) | 4 (476) | 2 (283) | 1 (400) | 7 (345, 328) | 1 (200, 400) | 0 | 2 (566, 400, 400) | 0 | 17 (74) |
| Total (70) | 7 (594) | 14 (345) | 1 (400) | 23 (400, 438) | 2 (283, 283) | 2 (1,131, 283, 566) | 5 (400, 696, 264) | 1 (1,600, 800, 1,600, 400) | 55 (79) |
Seroconversion was defined as a fourfold or greater rise in the titer of NtAbs in comparisons of the acute- and convalescent-phase sera. The GMTs for the strains indicated in the boxheads are shown sequentially in the body of the table. The G and P serotypes of the reference strains are as follows: for Wa (G1, P1A), for S2 (G2, P1B), for P (G3, P1A), and for ST3 (G4, P2A).