Table 1.
Main characteristics of the PWH patients and controls included in this study.
| All PWH N = 24 |
Frail-PWH N = 7 |
Non-Frail-PWH N = 17 |
Healthy Controls N = 12 |
p | ||
|---|---|---|---|---|---|---|
| Prefrail N = 9 |
Robust N = 8 |
|||||
| Sex at birth (Women/Men) | 4 W/20 M | 2 W/5 M | 2 W/7 M | 0 W/8 M | 4 W/8 M | |
| Age (years) Media (SD) |
61.9 (7.6) | 60 (3.9) | 65.3 (10.9) | 59.7 (4.2) | 60.6 (6.1) | 0.245 |
| Years living with known HIV Media (SD) |
16.5 (7.7) | 19.8 (6.5) | 17.5 (8.5) | 12.5 (6.6) | - | 0.164 |
| CD4+ nadir cells/mm3 Median (IQR) |
170.6 (154) | 171 (141.2) | 116.6 (105.6) | 231 (200) | - | 0.325 |
| Current CD4+ (cells/mm3) Media (SD) |
589.2 (342.1) | 662.8 (579.4) | 523.7 (207.8) | 598.5 (191) | - | 0.737 |
| Rate CD4/CD8 Median (IQR) |
0.87 (0.5) | 0.70 (0.3) | 0.74 (0.3) | 1.1 (0.6) | - | 0.124 |
| Diagnosed with depression (N) | 7 | 3 | 2 | 2 | - | 0.634 |
| Polypharmacy * (N) | 12 | 6 | 5 | 1 | - | 0.017 |
| BMI kg/m2 (N) | - | 0.293 | ||||
| <25 | 15 | 5 | 6 | 4 | ||
| 25–29 | 5 | 0 | 3 | 2 | ||
| >29 | 4 | 2 | 0 | 2 | ||
* Polypharmacy was defined as taking at least six or more comedications (excluding antiretroviral treatment).