Table 2.
Relative abundance (%), expressed as median and interquartile ranges, of the most abundant genera and phyla detected in the two groups (PWH and control) analyzed in this study.
| Control | PWH | ||||
|---|---|---|---|---|---|
| Phyla/Genera | N (%) a | Median (IQR) | N (%) | Median (IQR) | p-Value * |
| Firmicutes/Bacillota | 12 (100%) | 73.27 (67.71–77.6) | 24 (100%) | 74.51 (66.49–80.73) | 0.730 |
| Faecalibacterium | 12 (100%) | 9.25 (8.4–14.04) | 24 (100%) | 9.1 (5.07–15.04) | 0.560 |
| Blautia | 12 (100%) | 7.16 (5.82–8.48) | 24 (100%) | 11.18 (9.53–14.57) | <0.001 |
| Ruminococcus | 12 (100%) | 9.99 (8.12–14.64) | 24 (100%) | 9.08 (6.42–11.71) | 0.500 |
| Clostridium | 12 (100%) | 5.49 (4.17–7.21) | 24 (100%) | 3.08 (2.42–3.72) | 0.005 |
| Collinsella | 10 (83.33%) | 2.59 (1.11–4.78) | 21 (87.5%) | 2.83 (0.67–7.56) | 0.450 |
| Coprococcus | 12 (100%) | 1.79 (0.79–3.13) | 22 (91.67%) | 2.54 (1.32–4.58) | 0.180 |
| Slackia | 12 (100%) | 3.23 (1.45–3.93) | 23 (95.83%) | 2.01 (0.38–3.88) | 0.180 |
| Oscillospira | 12 (100%) | 3.99 (2.5–4.49) | 23 (95.83%) | 1.32 (0.78–2.89) | 0.018 |
| Alkaliphilus | 11 (91.67%) | 3.44 (2.08–4.46) | 22 (91.67%) | 0.76 (0.33–2.13) | 0.010 |
| Catenibacterium | 2 (16.67%) | <0.01 (<0.01–<0.01) | 9 (37.5%) | <0.01 (<0.01–1.83) | 0.210 |
| Roseburia | 12 (100%) | 1.54 (0.86–2.49) | 22 (91.67%) | 1.21 (0.53–2.59) | 0.700 |
| Eubacterium | 9 (75%) | 0.57 (0.06–2.23) | 17 (70.83%) | 0.64 (<0.01–2.48) | 0.970 |
| Erysipelothrix | 10 (83.33%) | 0.55 (0.25–1.4) | 24 (100%) | 0.83 (0.39–1.65) | 0.250 |
| Dorea | 12 (100%) | 0.58 (0.35–0.71) | 23 (95.83%) | 0.9 (0.66–1.38) | 0.022 |
| Bacteroidetes/Bacteroidota | 12 (100%) | 10.11 (6.6–13.5) | 23 (95.83%) | 7.31 (1.86–9.81) | 0.072 |
| Bacteroides | 12 (100%) | 5.89 (4.36–8.97) | 21 (87.5%) | 1.54 (0.5–6.61) | 0.033 |
|
Proteobacteria/ Pseudomonota |
12 (100%) | 1.89 (1.45–5.5) | 24 (100%) | 1.55 (0.88–4.79) | 0.560 |
| Escherichia | 8 (66.67%) | 0.37 (<0.01–1.22) | 13 (54.17%) | 0.18 (<0.01–1.92) | 0.740 |
|
Actinobacteria/ Actinomycetota |
12 (100%) | 3.33 (1.36–6.68) | 19 (79.17%) | 1.29 (0.39–4.41) | 0.320 |
| Bifidobacterium | 12 (100%) | 3.21 (0.63–6.55) | 15 (62.5%) | 0.99 (<0.01–4.17) | 0.240 |
| Minor_phyla | 9 (75%) | 0.55 (<0.01–0.88) | 20 (83.33%) | 0.85 (0.3–2.23) | 0.310 |
| Akkermansia | 4 (33.33%) | <0.01 (<0.01–0.25) | 7 (29.17%) | <0.01 (<0.01–0.26) | 0.950 |
| Minor_genera | 12 (100%) | 13.87 (10.3–17.63) | 24 (100%) | 11.99 (8.66–19.25) | 0.750 |
| Unclassified_phyla | 12 (100%) | 7.21 (6.66–7.58) | 24 (100%) | 7.09 (6.46–7.66) | 0.700 |
| Unclassified_genera | 12 (100%) | 15.01 (13.96–15.5) | 24 (100%) | 12.22 (11.16–14.94) | 0.210 |
a: Number of samples in which the phylum/genus was detected (relative frequency of detection). * Wilcoxon rank test.