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. 2023 Aug 18;13(8):1262. doi: 10.3390/biom13081262

Figure 1.

Figure 1

Scheme summarizing main endogenous and exogenous sources of ROS and RNS in the RBCs as well as the principal antioxidant actors. HbO2: Oxyhemoglobin; MetHb: methemoglobin; O2•−: superoxide anion; NO: nitric oxide; H2O2: hydrogen peroxyde; ONOO-: peroxynitrite; HO: hydroxyl radical; HOCl: hypochlorous acid; CO3•−: carbonate radical; NO2: nitrogen dioxide radical; superoxide dismutase: SOD; catalase: Cat; glutathione reductase: GR; reduced glutathione: GSH; glutathione peroxidase 1: Gpx1; thioredoxin reductase: TR; thioredoxin: Trx; Peroxiredoxin 2: Prx2.