Table 6.

Similarities in the a. a sequence of Proto-HLA, HLA class I heavy chains and β-chains of HLA-II.

HLA class I and Proto-HLA 34 V R F D S D . . . . . . E . R A . . . . . . . . E Y W 60

V: VALINE (NON-POLAR); R: ARGININE (+ CHARGE); F: PHENYLALANINE (NON-POLAR); D: ASPARTIC ACID (- CHARGE); S: SERINE (POLAR); E: GLUTAMIC ACID (- CHARGE); A: ALANINE (NON-POLAR); Y: TYROSINE (POLAR); W: TRYPTOPHAN (NON-POLAR)

ALLELES EXAMINED for Heavy Chains HLA-A ALLELES 1-504 HLA-B ALLELES 1-846 HLA-C ALLELES 1-277 HLA-G ALLELES 4 HLA-E ALLELES 2 34V R F D N D . . . . . . V . R A . . . . . . . . E Y W 60 HLA-F ALLELE 1 34L R F D S D . . . . . . E . R E . . . . . . . . Q Y W 60

HLA class II 38V R F D S D . . E . R A . . . . . . . . . E Y W 61 ALLELES EXAMINED for β-chain of HLA-II DRB ALLELES 1-512 DRB1*010101–1*030101–1*040101–1*070101–1*080101–1*090102–*110101, DRB1*130101–1*140101–1*150101–1*160101, DRB3*0106, DRB5*0102, DRB5*0202–5*0205; DQB ALLELES 1–71 DQB1*050101–DQB1*020101, DQB1*060101 36V R F D S D . . E . R A . . . . . . . . . E Y W 59 DPB ALLELES 1–123 DPB1*020102–1*030101–1*0402–1*0501–1*0601–1*0801–1*0901–1*1001, DPB1*1102, DPB1*1401, DPB1*1502, DPB1*1601–1*1701–1*1801–1*1901–1*200101 ---- 1*9901