Table 2.
Area under the ROC for the prediction of mortality at 28 days and 90 days.
| Analyses | |||||
|---|---|---|---|---|---|
| Univariate | Multivariate | ||||
| Biomarker or Clinical Score | Patients (N) | AUROC | OR IQR (95% CI) | OR IQR (95% CI) | |
| M28d | MR-proADM | 284 | 0.57 [0.45–0.69] | 1.08 [0.94–1.24] | 1.13 [0.82–1.56] |
| PCT | 274 | 0.47 [0.35–0.59] | 0.99 [0.98–1.01] | 0.99 [0.97–1.02] | |
| CRP | 237 | 0.49 [0.36–0.62] | 1.00 [0.99–1.01] | 1.01 [0.98–1.04] | |
| Lactate | 229 | 0.67 [0.55–0.79] | 1.13 [0.95–1.34] | 0.85 [0.49–1.49] | |
| SOFA | 284 | 0.63 [0.52–0.73] | 1.43 [1.03–1.97] | 1.63 [0.69–3.84] | |
| M90d | MR-proADM | 284 | 0.59 [0.49–0.68] | 1.08 [0.96–1.21] | 0.93 [0.72–1.20] |
| PCT | 274 | 0.44 [0.34–0.54] | 1.00 [0.99–1.00] | 0.99 [0.97–1.01] | |
| CRP | 237 | 0.54 [0.43–0.65] | 1.00 [0.99–1.01] | 1.00 [0.98–1.03] | |
| Lactate | 229 | 0.66 [0.55–0.77] | 1.25 [1.07–1.46] | 1.50 [0.90–2.50] | |
| SOFA | 284 | 0.62 [0.54–0.71] | 1.40 [1.08–1.81] | 1.31 [0.70–2.43] | |
Abbreviations: AUROC, area under the ROC; CI, confidence interval; OR, odds ratio; IQR, interquartile range; M28d, 28-day mortality; M90d, 90-day mortality. Multivariate analyses show the OR for predictive ability of every biomarker when combined between themselves and the inclusion of other variables: age, SOFA, APACHE II, and nosocomial infection.