Table 3.
Multivariate Cox model analyzing the effects of all studied opioid and cannabinoid receptors on overall survival among patients with pancreatic adenocarcinoma. Abbreviations: HR = hazard ratio, CI = confidence interval, OGFR = opioid growth factor receptor, OPRM = mu opioid receptor, OPRD = delta opioid receptor, OPRK = kappa opioid receptor, OPRL = lambda opioid receptor, CB2 = cannabinoid receptor 2.
| HR | 95% CI | p-Value | |
|---|---|---|---|
| Age | 1.011 | 0.987–1.036 | 0.363 |
| Sex | 1.057 | 0.677–1.65 | 0.806 |
| OGFR | 0.435 | 0.264–0.717 | 0.001 |
| OPRM | 2.076 | 1.199–3.594 | 0.009 |
| OPRD | 2.264 | 1.334–3.843 | 0.002 |
| OPRK | 0.480 | 0.286–0.805 | 0.005 |
| OPRL | 3.017 | 1.344–6.775 | 0.007 |
| CB2 | 0.538 | 0.333–0.869 | 0.011 |