Table 4.
Multivariate Cox model analyzing the effects of all studied opioid and cannabinoid receptors on cancer-specific survival among patients with pancreatic adenocarcinoma. Abbreviations: HR = hazard ratio, CI = confidence interval, OPRM = mu opioid receptor, OPRD = delta opioid receptor, CB2 = cannabinoid receptor 2.
| HR | 95% CI | p-Value | |
|---|---|---|---|
| Age | 1.023 | 0.978–1.07 | 0.318 |
| Sex | 1.234 | 0.632–2.409 | 0.538 |
| Piritramide | 3.060 | 1.478–6.337 | 0.003 |
| OPRM | 0.203 | 0.055–0.750 | 0.017 |
| OPRD | 4.886 | 2.228–10.717 | <0.001 |
| CB2 | 0.185 | 0.079–0.435 | <0.001 |