TABLE 1.

Incidence and prevalence of molluscum contagiosum (MC)

STUDY (COUNTRY)	POPULATION	ANNUAL INCIDENCE (95% CI)	COMMENTS
Koning 19946 (Holland)	332,300 adults and children, male and female	2.4 per 1000 person-years; cumulative incidence 17 percent in those <15 years of age	Seasonal variations in infections noted with greater incidence in warmer months.
Pannell 20057 (United Kingdom)	Data since 1995; total 4,826,470 subjects, 910,894 of whom were <15 years of age	175 per 100,000 in 1994 and 261 per 100,000 in 2000; incidence rate for those <15 years of age was 1,265 per 100,000 in 2000.	Maximum incidence occurred in preschoolers (ages 1–4 years); the cumulative incidence in children <15 years of age was 16.9 and 17.0 percent for male and female patients, respectively.
Reynolds 2009 8 (Indigenous natives of United States [American Indians and Alaska Natives])	13,711 patients (7,275 female)	20.15 per 10,000 from 2001 to 2005 (all ages); 102.98 per 10,000 for preschoolers (<5 years of age)	Rates are similar to US general population; very few studies examine epidemiology of MC in specific populations.
McCollum 20149 (Indigenous natives of United States [American Indians])	Case control study of 84 pediatric cases and 109 controls (<5 years of age); another study used data from 175 cases (<5 years of age) to compare with the 84 cases above.	Overall incidence: 68.5 per 10,000.	51.4% of cases had pre-existing eczema or dermatitis
Dohil 200510 (United States)	Retrospective chart review of 302 pediatric patients seen over eight months at 3 rural clinics	All patients had MC	63% had >15 lesions; 24% of patients had history of atopic dermatitis and were more likely to have a higher number of lesions.
Villa 2010 (Spain)11	20-year study; 12,424 adult patients; sexually transmitted	Incidence 2.7%, yearly distribution ranging 0–6.8%	Three-fold increase in incidence from 1988 to 1997 (1.3%) to 1998 to 2007 (4.0%), p<0.001

CI: confidence interval