FIG. 1.

Growth inhibition of encapsulated (NIH 37) and acapsular (NIH 3413) C. neoformans by human microglia. Growth inhibition is expressed as percent growth relative to cryptococcal growth at 24 h in cultures that did not contain microglia (control). Microglia were either not treated with cytokines or stimulated with IFN-γ (200 U/ml), GM-CSF (10 ng/ml), or a combination of both cytokines for 24 h prior to constitution of phagocytosis mixtures. Data represent means ± standard errors of the means of five (NIH 37) and three (NIH 3413) separate experiments with cells from different brain tissue specimens.