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. 2023 Aug 10;13(16):2642. doi: 10.3390/diagnostics13162642

Table 2.

Summary of OCT features compared with clinical appearance for different forms of OLP in comparison to leukoplakia and OSCC by means of a clinical study of N = 15 patients.

Pathology Clinical Appearance OCT Features
Reticular OLP increased EP surface reflectivity
homogeneous smooth surface reduced LP reflectivity
whitish keratinization limited BM visibility
inconspicious vessel network
Reticular atrophic OLP EP surface hyperreflectivity
inhomogeneous OM surface reduced EP thickness
whitish reticular keratinization reduced LP reflectivity
marginal reddened surface vague BM visibility
reduced layer differentiation
reduced nb. of large vessels
Atrophic OLP EP hyporeflectivity
inhomogeneous OM surface no BM visibility
predominant reddened surface no layer differentiation
enhanced vessel network
Atrophic erosive OLP EP hyperreflectivity
hyperkeratinization reduced EP thickness
ulcerative open wounds limited BM visibility
fibrin layer reduced layer differentiation
reduced nb. of large vessels
Plaque-like OLP hyperreflective layer at EP
hyperkeratinization no BM visibility
large whitish homogenous OM no layer differentiation
no vessel network identification
Leukoplakia hyporeflective surface
homogenous/inhomogeneous distinct shadowing
closed hyperkeratinization/ no BM visibility
interrupted hyperkeratinization no layer differentiation
no vessel network identification
OSCC hyperreflective EP surface
uneven interrupted surface strongly reduced imaging depth
floe-like hyperkeratinization cloud-like layered structure
distinct ulceration distinct shadowing
no BM and layer visibility
no vessel network identification