Table 2.

AJCC 8th staging classification of PanNET [58].

T1	Tumor limited to the pancreas, <2 cm
T2	Tumor limited to the pancreas, 2–4 cm
T3	Tumor limited to the pancreas, >4 cm, or invading the duodenum or common bile duct
T4	Tumor invades adjacent structures *
N0	No regional lymph node metastasis
N1	Regional lymph node metastasis
M0	No distant metastasis
M1	Distant metastasis

* Adjacent structures that can be involved in PanNETs include the stomach, spleen, colon, adrenal gland, or the walls of large vessels such as the celiac axis or superior mesenteric artery.