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. 2023 Aug 8;12(16):2022. doi: 10.3390/cells12162022

Figure 3.

Figure 3

Growth rate of A431 cells in the presence of cetuximab and human serum. (a) Growth medium is supplemented with 1 ug/mL cetuximab and 5% human donor serum samples plus 5% FBS or 10% FBS (FBS). (b) Growth medium is supplemented with increasing concentrations of cetuximab (0.1–6 µg/mL) and 5% human serum samples (sm1, sd12, and sd19) plus 5% FBS or 10% FBS (FBS). Bars represent the average cell growth rate for each donor sample calculated from three replicates normalized to no-drug conditions with FBS-only growth media (no-drug). Asterisks stand for statistically significant differences between FBS + cetuximab and Human serum + cetuximab samples: *, p < 0.05; **, p < 0.01; ***, p < 0.001. Dose–response curves for each donor sample calculated from three replicates normalized to no-drug conditions with FBS-only growth media.