Figure 3.

Cell viability of human small intestinal epithelial cells treated with psilocybin combined with transient receptor potential channel ligands. Graphs show the cell viability after 24, 48, 72, and 96 h of exposure to psilocybin combined with (A) capsaicin, (B) curcumin, or (C) eugenol. Cell viability was quantified by the MTT assay with the absorbance at 595 nm. Data were analyzed with one-way ANOVA followed by a Dunnett’s post hoc test compared to the vehicle. Bars represent the mean ± SD. Significance is indicated using the following scale: * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001. Cap, capsaicin; Cur, curcumin; Eug, eugenol; Psi, psilocybin.