Drug/Treatment |
MOA |
Status |
Conditions |
Aduhelm (aducanumab) |
A monoclonal antibody that targets beta-amyloid plaques in the brain |
Approved in June 2021 |
Mild cognitive impairment due to AD or mild AD |
Gantenerumab |
A monoclonal antibody that targets beta-amyloid plaques in the brain. |
Phase III clinical trials |
Mild AD |
Donanemab |
A monoclonal antibody that targets a modified form of beta-amyloid called N3pG |
Phase III clinical trials |
Early AD |
Tauvid Imaging (flortaucipir F18) |
A diagnostic imaging agent that targets tau protein |
Approved on May 2020 |
Detection of tau pathology in the brain |
Leqembi (Lecanemab) |
Remove sticky clumps of the toxic protein amyloid-β from the brain. |
Approved on 6 January 2023 |
Alzheimer’s disease |