TABLE 2.
Subgroup analysis of the relationship between BBOX1-AS1 expression and OS.
Variable | Total cases (n) | HR 95% CI | p | I2 (%) | Model |
---|---|---|---|---|---|
Overall survival | 562 | 2.30 [1.99, 2.67] | <0.00001 | 15 | Fixed |
Cancer types | |||||
NSCLC | 211 | 2.24 [1.71, 2.93] | <0.00001 | 0 | Fixed |
ESCC | 168 | 2.62 [2.10, 3.28] | <0.00001 | 11 | Fixed |
Other cancers | 183 | 1.92 [1.44, 2.56] | <0.00001 | 25 | Fixed |
Sample size | |||||
≥80 | 318 | 1.98 [1.59, 2.46] | <0.00001 | 0 | Fixed |
<80 | 244 | 2.61 [2.14, 3.19] | <0.00001 | 0 | Fixed |
Extracted method | |||||
Indirectly | 337 | 2.10 [1.73, 2.57] | <0.00001 | 0 | Fixed |
Directly | 225 | 2.57 [2.06, 3.20] | <0.00001 | 28 | Fixed |
Abbreviations: NSCLC, non–small-cell lung cancer; ESCC, esophageal squamous cell cancer.