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. 2023 Aug 24;13:27. doi: 10.5334/tohm.773

Table 3.

A review of the approach of the first injection of botulinum toxin in the treatment of Parkinson’s tremor.


AUTHOR, YEAR INDEX ECR ECU EDC EPL EIP FCR FCU FDL FPL FDP FDS FPB

Jankovic & Schwartz, 1991

Trosch. R.M, et al., 1994 No. 9 5 2 10 9

Dose 11.92 ± 3.84 11.67 ± 3.54 26.67 ± 22.55 18.21 ± 6.68 17.31 ± 6.96

Pullman, 1996 20.4 ± 14.2 15.8 ± 7.0 16.3 ± 5.5 6.5 ± 5.8 5.8 ± 2.8 25.6 ± 13.2 26.0 ± 16.7 53.3 ± 15.3 19.6 ± 7.2 30.6 ± 8.7 17.6 ± 9.4

Henderson, 1996

Rahimi. F. et al., 2013 No. 5 5 4 4 1 1

Dose 22 ± 3 22 ± 3 22 ± 3 22 ± 3 10 15

Rahimi. F. et al., 2015 No. 24 28 24 28

Dose 18.5 ± 8.2 16.8 ± 6.7 16.3 ± 7.0 16.8 ± 6.7

Samotus. O, et al., 2017

Mittal, S. O., et al., 2017 No. 19 10 18 27 25 7 6 11

Dose 5–10 5–10 5–10 10–15 10–20 10 10–20 5–10

Niemann & Jankovic, 2018 6 6

Kreiser, 2019

AUTHOR, YEAR INDEX PT PQ BICEPS TRICEPS SUP BRACHORADIALIS PECTORALIS MAJOR TERES MAJOR DELTOLID SUPRASPINATUS APB OPPONENS POLLICIS TOTAL

Jankovic & Schwartz, 1991 1

Trosch. R.M, et al., 1994 No. 1 2 2 12

Dose 35.00 ± 7.07 63.23 ± 15.28 52.50 ± 23.98 107.50 ± 50.56

Pullman, 1996 22.3 ± 6.2 17.9 ± 4.3 96.7 ± 32.7 58.6 ± 15.7 32.5 ± 14.7 51.4 ± 9.0 67.0 ± 27.3 65.2 ± 18.0 108.1 ± 24.6 3.1 ± 1.3 4.4 ± 1.3

Henderson, 1996

Rahimi. F. et al., 2013 No. 4 1 1 4 7

Dose 21 ± 3 50 50 19 ± 3 97 ± 52

Rahimi. F. et al., 2015 No. 25 25 23 10 22 1 9 6 4 5 28

Dose 17.4 ± 5.1 16.0 ± 4.9 33.9 ± 10.3 29.5 ± 10.1 17.3 ± 4.5 20.0 ± 0.0 33.3 ± 8.7 25.8 ± 6.7 30.0 ± 9.4 28.0 ± 2.4 174.1 ± 66.8

Samotus. O, et al., 2017

Mittal, S. O., et al., 2017 No. 25 23 3 5 6 1

Dose 10–20 10–15 10 10 5–10 5

Niemann & Jankovic, 2018 47.9 ± 11.5

Kreiser, 2019

Note All values are presented as mean ± standard deviation.

A tick sign indicates that the injection has been given in that muscle.

The results are related to the main injection and Booster injection, so in cases where even one person was injected, the indicators could be calculated.

Abbreviations No: the number of injected people; ECU: extensor carpi ulnaris; ECR: extensor carpi radialis; EDC: extensor digitrorum communis; FCU: flexor carpi ulnaris; FCR: flexor carpi radialis; FDL: flexor digitorum longus; FPL: flexor pollicis longus; EIP: extensor indicisproprius; EPL: extensor pollicis longus; FDP: flexor digitorum profunds; FDS: Flexor digitorum subllmis; FPB: Flexor pollicis brevis; PT: Pronator teres; PQ: Pronator quadratus; SUP: supinator; APB: Abductor pollicis brevis.