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. 2023 Jan 24;6(1):2118. doi: 10.23889/ijpds.v8i1.2118

Table 2: Measures of agreement for each acute serious outcome between the EHR (MedicineInsight) algorithms and linked (Reference) data.

Study population N=274,420 Acute Pancreatitis Myocardial Infarction Stroke Suicide VTE*
Reference+ HER+ (True positive) 79 773 655 177 486
Reference- HER+ (False positive) 26 430 739 406 904
Reference+ EHR- (False negative) 471 2,405 1,704 1,189 468
Reference- EHR- (True negative) 273,844 270,812 271,322 272,648 272,562
Sensitivity (95 % CI) 14.4 (10.5, 18.2) 24.3 (22.0, 26.7) 27.8 (25.6, 30.0) 13.0 (9.8, 16.2) 50.9 (47.0, 55.0)
Specificity (95 % CI) 100.0 (100.0, 100.0) 99.8 (99.8, 99.9) 99.7 (99.7, 99.8) 99.9 (99.8, 99.9) 99.7 (99.6, 99.7)
PPV (95 %CI) 75.2 (67.3, 83.1) 64.3 (59.8, 68.7) 47.0 (43.2, 50.8) 30.4 (27.3, 33.4) 35.0 (31.4, 38.5)
NPV (95 % CI) 99.8 (99.8, 99.9) 99.1 (90.0, 99.3) 99.4 (99.3, 99.5) 99.6 (99.5, 99.6) 99.8 (99.8, 99.9)
PoA (%) 99.8 99.0 99.1 99.4 99.5

*Venous Thromboembolism.