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. 2023 Jul 29;14(8):1559. doi: 10.3390/genes14081559

Figure 2.

Figure 2

ATL2-2 mRNA expression levels were higher in estrogen-receptor-negative tumors as compared to estrogen-receptor-positive tumors. A correlation analysis between ATL2-2 mRNA levels and estrogen receptor status was performed in Cohort 1, Cohort 2, TCGA, and METABRIC. The number of estrogen-receptor-negative and -positive tumors are shown below each boxplot. The difference in ATL2-2 expression between the estrogen-receptor-negative and -positive categories was calculated with a t-test with unequal variance. Cohort 1: p = 0.089, Cohort 2: p = 4 × 10−5, TCGA: p = 0.083, METABRIC: p = 2.2 × 10−16.