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Proliferative pathways were enriched in tumors that express high ATL2-2 mRNA levels. Gene set enrichment analysis was used to analyze which Hallmark pathways were upregulated in tumors with high ATL2-2 mRNA levels. The results show the top three pathways identified in the whole METABRIC cohort, which were also the only three pathways observed in estrogen-receptor-positive luminal B tumors in both METABRIC and TCGA cohorts.
