TABLE 4.
Representative diagnostic accuracy values for lobar power ratios.
| Cutoff | Sensitivity | Specificity | Youden index | PPV | NPV | ||
|---|---|---|---|---|---|---|---|
| Anterior | ABR | ≤1.02 (0.77–1.28) | 65.2 (49.8–78.6) | 61.3 (49.4–72.4) | 0.266 (0.103–0.381) | 62.8 (54.2–70.6) | 63.8 (53.3–73.1) |
| ATR | ≤0.82 (0.77–1.14) | 73.9 (58.9–85.7) | 48.0 (36.3–59.8) | 0.219 (0.098–0.351) | 58.7 (51.9–65.2) | 64.8 (51.7–76.0) | |
| TBR | ≤0.98 (0.82–1.60) | 28.3 (16.0–43.5) | 89.3 (80.1–95.3) | 0.176 (0.080–0.250 | 72.6 (54.3–85.5) | 55.5 (50.5–60.3) | |
| Central | ABR | ≤0.87 (0.70–0.99) | 50.0 (34.9–65.1) | 88.0 (78.4–94.4) | 0.380 (0.188–0.483) | 80.6 (67.9–89.1) | 63.8 (56.6–70.4) |
| ATR | ≤0.96 (0.84–1.22) | 60.9 (45.4–74.9) | 54.7 (42.7–66.2) | 0.155 (0.081–0.213) | 57.3 (48.9–65.4) | 58.3 (48.0–67.9) | |
| TBR | ≤0.95 (0.81–1.31 | 54.4 (39.0–69.1) | 76.0 (64.7–85.1) | 0.304 (0.148–0.444) | 69.4 (58.3–78.6) | 62.5 (54.2–70.0) | |
| Frontal | ABR | ≤0.99 (0.85–1.04) | 65.2 (49.8–78.6) | 70.7 (59.0–80.6) | 0.359 (0.156–0.466) | 69 (59.6–77.0) | 67 (57.1–75.6) |
| ATR | ≤0.80 (0.65–0.93) | 58.7 (43.2–73.0) | 61.3 (49.4–72.4) | 0.200 (0.092–0.314) | 60.3 (51.1–68.8) | 59.8 (50.2–68.7) | |
| TBR | ≤0.97 (0.81–1.31 | 30.4 (17.7–45.8) | 93.3 (85.1–97.8) | 0.238 (0.148–0.444) | 82 (63.8–92.2) | 57.3 (52.3–62.1) | |
| Occipital | ABR | ≤1.09 (0.84–1.45) | 71.7 (56.5–84.0) | 54.7 (42.7–66.2) | 0.264 (0.111–0.373) | 61.3 (53.8–68.3) | 65.9 (53.9–76.2) |
| ATR | ≤1.35 (0.84–1.22) | 78.3 (63.6–89.1) | 6.7 (2.2–14.9) | 0.151 (0.082–0.213) | 45.6 (41.6–49.7) | 23.5 (10.1–45.7) | |
| TBR | ≤0.75 (0.70–1.18) | 39.1 (25.1–54.6) | 92 8 (83.4–97.0) | 0.311 (0.167–0.447) | 83.67 (67.7–91.9) | 60.2 (54.3–65.8) | |
| Parietal | ABR | ≤1.03 (0.88–1.19) | 63.0 (47.5–76.8) | 72.6 (60.4–81.8) | 0.356 (0.162–0.464) | 69.2 (59.5–77.5) | 66.1 (56.6–74.5) |
| ATR | ≤1.01 (1.00–1.36) | 56.5 (41.1–71.1) | 70.7 (59.0–80.6) | 0.272 (0.137–0.446) | 65.8 (55.5–74.8) | 61.9 (53.1–70.0) | |
| TBR | ≤0.86 (0.77–1.27) | 41.3 (27.0–56.8) | 89.3 (80.1–95.3) | 0.306 (0.159–0.449) | 79.5 (64.9–89.0) | 60.3 (54.1–66.3) | |
| Temporal | ABR | ≤0.85 (0.76–1.12) | 47.8 (32.9–63.1) | 80.0 (69.2–88.4) | 0.278 (0.114–0.392) | 70.5 (58.1–80.5) | 60.5 (53.2–67.4) |
| ATR | ≤0.77 (0.72–1.03) | 34.8 (21.4–50.2) | 85.3 (75.3–92.4) | 0.201 (0.108–0.306) | 70.3 (54.7–82.3) | 56.7 (50.9–62.2) | |
| TBR | ≤1.00 (0.86–2.15 | 52.2 (36.9–67.1) | 70.7 (59.0–80.6) | 0.228–(0.1100.350) | 64 (53.2–73.6) | 59.6 (51.4–67.4) | |
Note: Data are expressed as mean (95% CI). Cutoff point, sensitivity, specificity, PPV, and NPV were measured at maximum Youden index after standardization of disease prevalence to 50%; 95% CI for cutoff point and Youden index was estimated with bootstrapping method (5000 iterations, 978 seeds); 95% binomial exact CI for sensitivity, specificity, PPV, and NPV was estimated by Delong's method.
Abbreviations: ABR, alpha/beta ratio; ATR, alpha/theta ratio; CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value; TBR, theta/beta ratio.