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. 2023 Aug 16;14(8):1630. doi: 10.3390/genes14081630

Table 1.

Core genes and variants associated with behaviour traits.

Behaviour Trait Core Genes Genome Variants References
Alcohol Use ADH1B, ADH1C, ALDH2 rs1229984, rs698, rs671 [30,31,44]
Smoking CHRNA5, CHRNA3, CHRNB4 rs16969968, rs1051730 [38,45,46,47]
Drug Use DRD2, OPRM1, ABCB1 rs1800497, rs1799971, rs1045642 [48,49,50]
Stress FKBP5, CRHR1, NR3C1 rs1360780, rs110402, rs6195 [51,52,53]
Anxiety SLC6A4, HTR1A, HTR2A rs6295, rs6311, rs6313 [54,55,56]
Fearfulness SLC6A4, COMT, MAOA rs4680, rs6323, rs6354 [57,58,59]
Impulsivity DRD4, SLC6A4, COMT, HTR2A rs1800955, rs25531, rs4680 [40,41,60]
Lack of Sleep ABCC9, PER2, PER3, CRY1 rs11046209, rs934945, rs228697 [61,62,63]
Depression SLC6A4, BDNF, HTR2A rs25531, rs6265, rs6313 [42,64,65]