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. 2023 Aug 14;24(16):12776. doi: 10.3390/ijms241612776

Figure 4.

Figure 4

Pattern of proteoforms, mainly proteolytic fragments, originating from statherin (a), and the P-B peptide (b), characterized in human saliva by a top-down approach based on reversed-phase high pressure liquid chromatography-electrospray ionization tandem mass (RP-HPLC-ESI-MS/MS) analysis. The arrows indicate the main cleavage sites. The sequences recognized by furin-like convertase are evidenced in bold red, and the fragments derived by these cleavages are in shown in red.