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Significant reduction of the inward current detected in the U251 edge cells following the perfusion of a Na-free solution. (a) Experimental traces elicited by depolarizing the voltage steps from −120 mV to +40 mV before (black traces) and after local perfusion of the extracellular Na-free solution containing lithium chloride (LiCl, red traces) instead of sodium chloride (NaCl). (b) Mean I–V relationships before and after LiCl local perfusion (n = 5).
