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. 2021 Apr 20;104(2):00368504211010938. doi: 10.1177/00368504211010938

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Prognostic relevance of the genes correlated with CD133 expression in patients with PRCC: (a) Functional signaling pathway enrichment analysis of the top 200 genes which were most positively associated with CD133 expression in TCGA PRCC patients, (b) functional signaling pathway enrichment analysis of the top 200 genes which were most negatively associated with CD133 expression in TCGA PRCC patients, and (c) Kaplan–Meier survival analysis was used to determine the prognostic effects of p53 signaling pathway associated genes CCNB1, CCNB2, CCNE1, CDK1, CDK4, GTSE1, and RRM2 in PRCC patients. p values were generated from Log-rank test.