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. 2023 Aug 11;14:1237159. doi: 10.3389/fphys.2023.1237159

TABLE 1.

Semi quantitative scoring of the histopathology in the thyroid follicles, female gonads, and male gonads of Oreochromis niloticus exposed to Harness®.

Histopathological lesion Control Treated group
H1 H1Lyc H2 H2Lyc
Thyroid follicles
Colloid depletion of some follicles - ++ - +++ +
Increasing melanomacrophage centers - ++ - +++ +
Hypertrophic thyrocytes - + + +++ +
Hyperplastic follicles - + - +++ _
Gonad female
Displayed few atretic follicles - + - ++ -
Increasing number of oocytes - + - ++ -
Increasing number of atretic follicles - ++ + +++ +
Less number of the secondary growth phase - + - +++ +
Gonad male
Decrease in spermatozoa amount - + - ++ -
Increasing melanomacrophage centers - ++ - +++ +
Necrosis - + - ++ -

–, normal; +, mild (<10%); ++, moderate (10%–50%); +++, severe (>50%).