TABLE 1.
Semi quantitative scoring of the histopathology in the thyroid follicles, female gonads, and male gonads of Oreochromis niloticus exposed to Harness®.
| Histopathological lesion | Control | Treated group | |||
|---|---|---|---|---|---|
| H1 | H1Lyc | H2 | H2Lyc | ||
| Thyroid follicles | |||||
| Colloid depletion of some follicles | - | ++ | - | +++ | + |
| Increasing melanomacrophage centers | - | ++ | - | +++ | + |
| Hypertrophic thyrocytes | - | + | + | +++ | + |
| Hyperplastic follicles | - | + | - | +++ | _ |
| Gonad female | |||||
| Displayed few atretic follicles | - | + | - | ++ | - |
| Increasing number of oocytes | - | + | - | ++ | - |
| Increasing number of atretic follicles | - | ++ | + | +++ | + |
| Less number of the secondary growth phase | - | + | - | +++ | + |
| Gonad male | |||||
| Decrease in spermatozoa amount | - | + | - | ++ | - |
| Increasing melanomacrophage centers | - | ++ | - | +++ | + |
| Necrosis | - | + | - | ++ | - |
–, normal; +, mild (<10%); ++, moderate (10%–50%); +++, severe (>50%).