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. 2023 Aug 11;13:1204335. doi: 10.3389/fonc.2023.1204335

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Copyright © 2023 Chen, Wang, Wu, Lan and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DRAGcluster analysis. (A) Consensus matrix diagram defining the relevant regions of the two clusters. (B) PCA analysis shows significant differences between the two subtype groups. (C) K-M analysis shows the prognostic characteristics of patients in both subgroups. (D) Differences in clinicopathological features and expression levels of DRAGs between the two different subtypes. (E) GSVA of biological pathways between the two different subtypes, red and blue represent activating and inhibiting pathways, respectively. (F) The extent of infiltration of 23 immune cells in HCC subtypes. pca, principal component analysis; gsva, gene set variation analysis. ** represents P<0.01, *** represents P<0.001.