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Illustrative structure of anti-VEGF antibody-derived drugs. Molecular weights, clinical doses, and approximate molar amounts of clinical doses are summarized. Region of anti VEGF is indicated by yellow domains and region of anti-ANG2 is indicated by green. VH, variable region of heavy chain; VL, variable region of light chain; CH1, constant region 1 of heavy chain; CH2, constant region 2 of heavy chain; CH3, constant region 3 of heavy chain; CL, constant region of light chain.
