Table 2.
APLN expression a associated with clinical pathological characteristic (logistic regression).
| Characteristics | Odds ratio in APLN expression | Odds ratio (OR) | p Value |
|---|---|---|---|
| N stage (N1 vs N0) | 193 | 0.92 (0.50–1.71) | 0.801 |
| M stage (M1 vs M0) | 126 | 4.75 (1.13–32.42) | 0.055 |
| Clinical stage (stage II and stage III and stage IV vs stage I) | 297 | 1.91 (1.21–3.05) | 0.006 b |
| Histological type (squamous vs adenosquamous cell carcinoma) | 304 | 1.32 (0.73–2.43) | 0.362 |
| Histologic grade (G3 and G4 vs G1 and G2) | 272 | 1.67 (1.03–2.72) | 0.037 b |
| PIK3CA status (Mut vs WT) | 286 | 1.09 (0.65–1.83) | 0.737 |
| Primary therapy outcome (PD, SD, and PR vs CR) | 217 | 2.14 (1.03–4.59) | 0.045 b |
CR: complete response; PD: progressive disease; PR: partial response; SD: stable disease.
a
Categorical dependent variable, greater or less than the median expression level.
b
Statistically significant.