Table 4.
Stepwise Multivariate Analysis for Hernia Recurrence Versus Patient Demographics, Comparing Demographics Across Mesh Type, Component Separation (Closure Type), and Demographics Combined With Mesh Type and Closure Type
| Recurrence | No | Yes | OR (Univariable) | Demographics | Demographics and Mesh Type | Demographics and Closure Type | Demographics, Mesh Type, and Closure Type |
|---|---|---|---|---|---|---|---|
| OR (Multivariable) | OR (Multivariable) | OR (Multivariable) | OR (Multivariable) | ||||
| P4HB, N (%) | 27 (50.9) | 4 (20.0) | 0.241 (0.071–0.816, P = 0.022) | 0.203 (0.051–0.814, P = 0.024) | 0.150 (0.033–0.680, P = 0.014) | ||
| Component separation (%) | 13 (24.5) | 6 (30.0) | 1.319 (0.421–4.135, P = 0.635) | 1.44 (0.391–5.329, P = 0.582) | 2.789 (0.597–13.026, P = 0.192) | ||
| Mean age, years (SD) | 55.8 (12.9) | 53.4 (9.4) | 0.982 (0.940–1.027, P = 0.432) | 0.974 (0.920–1.032, P = 0.375) | 0.976 (0.918–1.038, P = 0.439) | 0.972 (0.916–1.030, P = 0.338) | 0.970 (0.912–1.033, P = 0.343) |
| Gender, N (%) | 36 (67.9) | 14 (70.0) | 1.102 (0.361–3.366, P = 0.865) | 0.553 (0.137–2.237, P = 0.406) | 0.705 (0.157–3.164, P = 0.648) | 0.533 (0.130–2.183, P = 0.382) | 0.669 (0.912–1.033, P = 0.343) |
| African American, N (%) | 16 (30.2) | 5 (25.0) | 0.771 (0.239–2.483, P = 0.663) | 1.090 (0.261–4.545, P = 0.906) | 1.117 (0.248–5.035, P = 0.886) | 1.084 (0.258–4.561, P = 0.912) | 1.145 (0.251–5.220, P = 0.861) |
| BMI (kg/m2), mean (SD) | 31.2 (7.0) | 30.3 (6.7) | 0.981 (0.907–1.061, P = 0.625) | 0.979 (0.889–1.079, P = 0.675) | 0.963 (0.865–1.072, P = 0.494) | 0.983 (0.892–1.084, P = 0.737) | 0.971 (0.872–1.082, P = 0.600) |
| Hypertension (%) | 40 (75.5) | 15 (75.0) | 0.975 (0.297–3.205, P = 0.967) | 1.089 (0.253–4.692, P = 0.909) | 1.080 (0.239–4.888, P = 0.920) | 1.100 (0.251–4.810, P = 0.900) | 1.156 (0.242–5.511, P = 0.856) |
| Diabetes (%) | 18 (34.0) | 7 (35.0) | 1.047 (0.355–3.085, P = 0.934) | 0.969 (0.272–3.455, P = 0.962) | 0.779 (0.200–3.037, P = 0.719) | 0.982 (0.275–3.514, P = 0.978) | 0.766 (0.193–3.044, P = 0.705) |
| Alcohol use, N (%) | 16 (30.8) | 7 (35.0) | 1.211 (0.407–3.608, P = 0.730) | 1.204 (0.304–4.769, P = 0.791) | 1.562 (0.361–6.759, P = 0.551) | 1.212 (0.307–4.775, P = 784) | 1.633 (0.372–7.169, P = 0.516) |
| Smoker, N (%) | 24 (45.3) | 14 (70.0) | 2.819 (0.940–8.459, P = 0.064) | 3.473 (0.984–12.265, P = 0.053) | 4.094 (1.074–15.606, P = 0.039) | 3.563 (1.005–12.631, P = 0.049) | 4.313 (1.118–16.632, P = 0.034) |
| Liver disease, N (%) | 26 (49.1) | 12 (60.0) | 1.558 (0.548–4.426, P = 0.405) | 1.447 (0.385–5.441, P = 0.584) | 1.025 (0.253–4.143, P = 0.973) | 1.507 (0.394–5.768, P = 0.549) | 1.068 (0.259–4.400, P = 0.927) |
| Immunocompromised, N (%) | 28 (52.8) | 14 (70.0) | 2.083 (0.695–6.245, P = 0.190) | 1.933 (0.537–6.964, P = 0.313) | 1.963 (0.522–7.382, P = 0.318) | 1.820 (0.489–6.772, P = 0.372) | 1.743 (0.441–6.895, P = 0.428) |
BMI indicates body mass index.