I NEED HELP, a simple mnemonic to remember the “red flags” for the patient’s referral to an advanced heart failure center. I: Previous or ongoing requirement of inotropes or inodilators. N: NYHA class III-IV, high natriuretic plasma levels, E: worsening kidney or liver function due to heart failure, E: left ventricular ejection fraction <20%, D: recurrent appropriate defibrillator shocks, H: 2 or more episodes of worsening heart failure, E: persisting fluid overload and/or increasing diuretic requirement, L: systolic blood pressure persistently <90–100 mm Hg, P: intolerance to disease-modifying drugs.