Intrinsic renal disease |
The presence of hypertension, diabetes mellitus, or lupus increases the possibility of irreversible kidney disease. |
eGFR |
Perform two independent measurements for eGFR at least two weeks apart with the CKD-EPI formula. |
Proteinuria |
Proteinuria is indicative of intrinsic kidney damage. |
Kidney size and parenchymal evaluation |
The shrunken size of the kidney and the presence of cortical scarring indicate long-term intrinsic and irreversible kidney disease. |
Improved kidney function after hemodynamic optimizations |
Increased eGFR after the use of inotropes/vasodilators/diuretics is indicative of functional kidney dysfunction. |