Table 2.
List of all input variables and their univariate Pearson correlation with the measures of the diffusion capacity of the lung (n = 45). The demographic variables and the total volume of residual lesions on CT were considered potential confounders in the multivariate analysis (Table 3). Definition of abbreviations: VA—alveolar volume; CT—computed tomography; TBV—total intraparenchymal blood vessel volume by CT; TissueM—total non-vessel lung mass by CT; PDm—mode of the histogram of parenchymal radiodensity values on CT.
| Input Variables | DLCO_adj (% Predicted) | KCO_adj (% Predicted) |
|---|---|---|
| VA (% predicted) | r = 0.52, p < 0.001 | r = −0.39, p = 0.008 |
| TBV | r = 0.41, p = 0.005 | r = 0.13, p = 0.39 |
| Blood vessel volume fraction | r = 0.30, p = 0.046 | r = 0.36, p = 0.014 |
| TissueM | r = 0.29, p = 0.048 | r = −0.08, p = 0.58 |
| PDm | r = 0.21, p = 0.16 | r = 0.33, p = 0.027 |
| Total volume of residual lung lesions on CT | r = −0.21, p = 0.17 | r = −0.29, p = 0.051 |
| Age | r = −0.11, p = 0.47 | r = −0.05, p = 0.73 |
| Sex | r = 0.02, p = 0.88 | r = 0.14, p = 0.34 |
| Vaccination status | r = 0.13, p = 0.40 | r = 0.02, p = 0.91 |
| Disease severity in the acute phase | r = −0.08, p = 0.62 | r = −0.01, p = 0.94 |
| Days between symptom onset and CT date | r = −0.07, p = 0.63 | r = −0.29, p = 0.051 |