TABLE 3.
Pooled Incidence of Complications Following IPAA With 95% CI
Number of Studies | Number of Patients | Pooled Incidence (%) (95% CI) | Range (%) | |
---|---|---|---|---|
Pouch failure | 30 | 22,869 | 6.7 (5.28–8.44) | 2.4–30.0 |
Pouch failure ≥5 yrs FU | 19 | 12,994 | 7.7 (5.56–10.59) | 2.4–30.0 |
Pouch failure ≥10 yrs FU | 11 | 5314 | 10.3 (7.24–14.30) | 2.4–30.0 |
Anastomotic leakage | 16 | 14,479 | 6.3 (4.50–8.83) | 0.8–16.9 |
Pelvic sepsis | 16 | 14,884 | 9.2 (7.05–11.87) | 2.2–17.5 |
Fistula | 18 | 13,944 | 8.6 (6.07–11.94) | 0.8–29.5 |
Stricture | 15 | 4952 | 10.3 (6.63–15.60) | 0.8–33.6 |
Crohn’s disease de novo | 11 | 7115 | 4.0 (1.93–8.04) | 0.0–17.8 |
Pouchitis | 22 | 6856 | 30.0 (23.41–37.62) | 11.0–61.4 |
CI indicates confidence interval; FU, follow-up; IPAA, ileal pouch-anal anastomosis.