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. 2023 Aug 11;12(16):5231. doi: 10.3390/jcm12165231

Table 1.

Inflammatory markers are associated with various neurological conditions.

Si No Disease Findings
1 Multiple Sclerosis a. Caspase-1 and ASC (apoptosis-associated speck-like protein) in serum are predictors for the severity of the disease [124].
b. IL-1β, Caspase-1 ↑, IL-18, in CSF and PBMC (Peripheral Blood Mononuclear Cells) [125].
2 Alzheimer’s Disease a. IL-18, Caspase-1, ASC, and IL-1β, in PBMCs.
b. IL-1β, IL-18 in astrocytes, microglia, and neurons surrounding Aβ plaques [126,127].
3 Parkinson’s disease a. Caspase-1, IL-1β in the striatum and serum [128].
4 Neuropsychiatric disorder a. Increased activity of NLRP3 inflammasome [129,130,131].

↑—Increased serum levels.