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. 2023 Aug 9;14(8):697. doi: 10.3390/insects14080697

Figure 4.

Figure 4

Predictions of (rac-8) and compound 4 lactone derivative binding to TRP channels related to Drosophila suzukii and the species closely related to the Trichopria anastrephae parasitoid, Trichopria drosophilae. (A) Structures of active sites of the Drosophila suzukii TRP channel (TRPM, left panel) and Trichopria drosophilae TRP channels (TRPC, right panel) interacting with (rac)-8 (blue). (B) Structures of active sites of the D. suzukii TRP channel (TRPM, left panel) and Trichopria drosophilae TRP channels (TRPC, right panel) interacting with compound 4 (green). (C) Two-dimensional interaction map representations of D. suzukii and T. drosophilae TRP channels with (rac)-8. (D) Two-dimensional interaction map representations of D. suzukii and T. drosophilae TRP channels with compound 4. All detailed amino acids belonging to the lipid environment binding site are also represented. (For the interpretation of the references used to color in this figure legend, the reader is referred to the web version of this article).