Figure 4.
Significant interaction of genistin with (A) ER alpha (PDB ID-6CHZ) and (C) human epidermal growth factor receptor 2 (PDB ID-7PCD) The enlarged image illustrates the acceptor amino acid residues and hydrogen bonds donor in the junction cavity. The 2D image (B) ER alpha and (D) HER2 shows the genistin interacting with binding pocket residues as a protein inhibitor.