Table 1.
The trend in laboratory parameters in the cohort during pre- and postoperative follow-up
| Variables | Median (minimum–maximum) | P | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Preoperative | 2 weeks postoperative | 3 months postoperative | 6 months postoperative | 9 months postoperative | 12 months postoperative | ||
| Hb (g/dL) | 11.5 (10–12.2) | 10.3 (8–11.6) | 10.9 (8.5–12.4) | 10.8 (8.7–16.7) | 11.1 (9–12) | 11.9 (9.2–12.2) | 0.159 |
| TLC (109/L) | 11.6 (7–14.7) | 9.8 (8.6–12.9) | 9.2 (6–11.3) | 9.1 (5–12.1) | 8.5 (5.8–10) | 9 (7–11) | 0.173 |
| PLT (109/L) | 384 (170–564) | 376 (174–582) | 345 (174–488) | 318 (138–365) | 280 (102–369) | 286 (152–311) | 0.503 |
| INR | 1.09 (1–1.1) | 1.1 (1.1–1.13) | 1.1 (1–1.13) | 1.1 (1–1.13) | 1.1 (1.01–1.12) | 1.1 (1.07–1.12) | 0.194 |
| PC (%) | 90.6 (87–100) | 91 (84.7–97) | 90.3 (83.9–99) | 84 (64–99) | 87 (84–99) | 89 (79.5–96.5) | 0.099 |
| Bilirubin total | 11.9 (2.9–20.9) | 10.3 (2–21.4) | 10.5 (2.8–25.1) | 9.9 (2.7–17.9) | 9.7 (2.2–18.8) | 12.1 (9–24.7) | 0.121 |
| Bilirubin direct | 10 (1.5–19.2) | 5.6 (1.5–11.2) | 7.5 (1.6–14.5) | 6.5 (1.2–11.8) | 6.1 (1.36–12) | 7.9 (4.8–19.1) | 0.361 |
| AST (U/L) | 205 (31–336) | 181 (62–328) | 174 (56–639) | 183 (48–305) | 208 (167–263) | 249 (193–288) | 0.67 |
| ALT (U/L) | 145 (34–219) | 146 (44–363) | 138 (34–383) | 162 (31–251) | 230 (165–343) | 206 (167–263) | 0.361 |
| GGT (U/L) | 69 (22–574) | 70 (27–537) | 98 (23–637) | 91 (21–533) | 149 (39–517) | 68 (37–457) | 0.617 |
| ALP (U/L) | 593 (314–1113) | 324 (262–779) | 526 (257–1043) | 537 (323–1010) | 491 (347–1016) | 413 (330–330) | 0.267 |
| Albumin (mg/dL) | 3.4 (2.1–3.8) | 3.5 (3–4.9) | 3.5 (2.2–4.6) | 3.7 (2.6–4.83) | 3.6 (2.8–4.3) | 3.7 (2.9–3.9) | 0.059 |
| Bile salt (umol/L) | 154 (29.5–216) | 80.5 (18.4–110) | 80 (14–104) | 0.013* | |||
| Cholesterol (mg/dL) | 132 (76–734) | 100.5 (69–315) | 0.59 | ||||
P <0.05 was considered statistically significant, Hb: Hemoglobin, TLC: Total leucocyte count, PLT: Platelets, INR: Internationalized ratio, PC: Prothrombin concentration, AST: Aspartate aminotransferase, ALT: Alanine amino transferase, ALP: Alkaline phosphatase, GGT: Gamma-glutamyl transferase