Table 1.
Patient characteristics at admission
Variables of interest (normal range) | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 |
---|---|---|---|---|---|
Age (years) | 7 | 8 | 10 | 11 | 14 |
Sex | Female | Male | Female | Female | Female |
Acute severe COVID-19 or MIS-C | MIS-C | MIS-C | MIS-C | Acute severe COVID-19 | Acute severe COVID-19 |
Immediate underlying abdominal condition | Colitis | Ileitis | Acute edematous pancreatitis | Perforated appendicitis | Perforated appendicitis |
SARS-CoV-2 RTPCR | Negative | Negative | Positive | Positive | Positive |
Anti SARS-CoV-2 spike antibody IgG (<0.8 U/mL) | Positive (68.36) | Positive (91.4) | - | - | - |
CRP (<0.6 mg/dL) | 19.7 | 3.28 | 9 | 6.36 | 9 |
Procalcitonin (<0.5 ng/mL) | 9.49 | 0.29 | 0.15 | 29.99 | 0.24 |
D-dimer (<0.5 µg FEU/mL) | 4.89 | 2.23 | 31.23 | 10 | 4.91 |
Ferritin (13–150 ng/mL) | 231.4 | 118.4 | 233.7 | 15.95 | 140.2 |
LDH (85–227 U/L) | - | 178 | 415 | 447 | 573 |
Amylase (25–125) U/L | 27 | 36 | 66 | - | - |
Lipase (5–31) U/L | 77.8 | 11.2 | 76 | - | - |
Ultrasound/CT imaging | Mesenteric lymphadenopathy, hepatomegaly, colon wall edema, leukoencepahlitis | Hepatomegaly, ascites, small bowel wall edema, pleural effusion, pulmonary alveolar hemorrhage | Acute edematous pancreatitis, ascites, colon wall edema, mesenteric lymphadenopathy, bilateral renal pyramid hypoenhancement, pleural effusion | Perforated appendicitis | Perforated appendicitis, splenomegaly |
COVID-19: Coronavirus disease 2019, MIS-C: Multisystem inflammatory syndrome in children, SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2, RTPCR: Reverse transcription-polymerase chain reaction, CRP: C-reactive protein, FEU: Fibrinogen, CT: Computed tomography, LDH: Lactate dehydrogenase, IgG: Immunoglobulin G